Cemaloğlu, ReşitAsmafiliz, NuranTümer, YaseminHökelek, TuncerKılıç, ZeynelÇelik, Nejla NurAçık, LeylaGüzel, RemziyeErdal, Gülbahar Güzel2024-11-082024-11-082024Cemaloğlu, R., Asmafiliz, N., Tümer, Y., Hökelek, T., Kılıç, Z., Çelik, N. N. ve diğerleri. (2024). Phosphorus-nitrogen compounds: Part 76. design and syntheses of dispiro- and trispiro(N/N)cyclotriphosphazenes: Conformational and structural analyses, chirality, electrochemical, dye-sensitized solar cells, and bioactivity studies. Inorganic Chemistry, 63(39), 18389-18407.0020-1669https://pubs.acs.org/doi/10.1021/acs.inorgchem.4c02206https://hdl.handle.net/11468/28932The reactions of monospirocyclotriphosphazenes (1 and 2) with N-methyl-1,3-diaminopropane gave unsymmetrical cis-(3 and 5) and trans-(4 and 6) dispirocyclotriphosphazenes. Trans-cis-trans (tct) (7 and 11), cis-cis-cis (ccc) (8 and 12), trans-trans-cis (ttc) (9 and 13), and cis-trans-trans (ctt) (14) trispirocyclotriphosphazenes were obtained from the reactions of 3 and 5 and 4 and 6 with N-methyl-1,3-diaminopropane. cis-Dispirocyclotriphosphazenes (3 and 5) exist as “pseudomesoracemates”, while trans-dispirocyclotriphosphazenes (4 and 6) are in “racemates”. The existences of cis-3 and trans-4 as “pseudomesoracemate” and “racemate” were confirmed by 31P NMR spectra recorded by the addition of “chiral solvating agent (CSA)”. X-ray crystallography proved that the absolute configurations of each enantiomer of cis-5 and trans-6 are SS′ and RS′. Trispirocyclotriphosphazenes tct, ttc, ccc, and ctt exist as racemates, pseudomesoracemate, and meso forms. Furthermore, Hirshfeld surface analysis of the crystal structures of cis-5 and trans-6 revealed that the most significant contribution to crystal packing comes from H···H (58.2 and 57.6%, respectively). An oxidation-reduction wave was detected in the reversible cyclic voltammograms of the phosphazenes. The highest power conversion efficiency in dye-sensitized solar cell studies was obtained with cis-5. Additionally, trans-6 exhibited the lowest minimal inhibitory concentration value (78.1 μM) against Candida tropicalis, and it was observed to cleave pBR322 plasmid DNA.eninfo:eu-repo/semantics/closedAccessArticle63391838918407WOS:0013187101000012-s2.0-8520457473339301633Q1Q1