Synthesis of novel chiral C2-symmetric diaza-18-crown-6 ether derivatives and their enantioselective recognition of amino acid derivatives

Turgut, YDemirel, NHosgören, H2024-04-242024-04-2420061388-31271573-1111https://doi.org/10.1007/s10847-005-3125-1https://hdl.handle.net/11468/14694New chiral diaza-18-crown-6 ether derivatives, 5 and 6 were synthesized from (R)-(-)-2-amino-1-butanol. These chiral artificial receptors exhibit pronounced chiral recognition toward the enantiomers of L- and D- amino acid derivatives. The highest enantioselectivity was observed in the case of Trp-OMe center dot HCl (K-D/ K-L= 12.5).eninfo:eu-repo/semantics/closedAccessAmino AcidChiral Aza Crown EtherComplexationMolecular RecognitionSynthesis of novel chiral C2-symmetric diaza-18-crown-6 ether derivatives and their enantioselective recognition of amino acid derivativesSynthesis of novel chiral C2-symmetric diaza-18-crown-6 ether derivatives and their enantioselective recognition of amino acid derivativesArticle541-22933WOS:0002338767000052-s2.0-2914443720810.1007/s10847-005-3125-1Q2Q2