Prenatal diagnosis of fetal goiter and successful treatment with intraamniotic levothyroxine: a case report

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Tarih

2024

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Perinatal Medicine Foundation

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Objective: Fetal goiter is rare and may cause polyhydramnios, fetal growth restriction, and congenital hypothyroidism. We aimed to report a rare case of fetal goiter complicated by polyhydramnios in a pregnant woman. Case(s): A 32-year-old woman with a 32-week pregnancy was referred to us because of polyhydramnios. Ultrasound examination revealed fetal asymmetric growth restriction and severe polyhydramnios. The fetal stomach was smaller, and pharyngeal dilatation and approximately 50x45 mm fetal neck mass (goiter) were observed. Also, mild hypothyroidism was detected in maternal thyroid function tests. In-utero treatment was initiated with 200 µg of levothyroxine injected into the amniotic sac. This treatment was repeated every 10 days for 2 doses following the initial dose. After levothyroxine treatment, fetal goiter and amniotic fluid volume completely recovered until birth. Conclusion: Fetal goiter can be successfully treated with an intraamniotic injection of levothyroxine. © 2024 Perinatal Medicine Foundation.

Açıklama

Anahtar Kelimeler

Fetal goiter, intrauterine treatment, levothyroxine, prenatal diagnosis

Kaynak

Perinatal Journal

WoS Q Değeri

Scopus Q Değeri

Q4

Cilt

32

Sayı

2

Künye