The preventive effect on bone loss of 50-Hz, 1-mT electromagnetic field in ovariectomized rats

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dc.contributor.authorSert, C
dc.contributor.authorDeniz, M
dc.contributor.authorDüz, MZ
dc.contributor.authorAksen, F
dc.contributor.authorKaya, A
dc.date.accessioned2024-04-24T16:01:58Z
dc.date.available2024-04-24T16:01:58Z
dc.date.issued2002
dc.departmentDicle Üniversitesien_US
dc.description.abstractOsteoporosis is a common health problem, especially in the elderly and in women after menopause. Although there are some treatment methods, they impose serious side effects. Recently, the use of an electromagnetic field (EMF) has been a promising candidate for better treatment of osteoporosis. In the present study, we investigated the preventive effects of low-frequency (50 Hz), low-intensity (1 mT), and long-term (6 weeks) EMF on bone loss in ovariectomized rats. We used 18 female albino Wistar rats (8 unexposed and 10 exposed) to assess the effect of EMF. We examined the mineralization and the morphology of the tibia in control and EMF-exposed rats. The cortical thickness of the tibia was increased in EMF-exposed rats (P < 0.002). The levels of Na and K in the tibia were significantly increased in rats exposed to EMF (P < 0.001; P < 0.002, respectively). We also observed an increased blood alkaline phosphatase (ALP) level after EMF exposure (P < 0.05). No significant differences in the levels of Ca, Mg, Li, or creatine were found between the exposed and unexposed groups. Our data support the notion that an EMF may prove to be an effective treatment method for osteoporosis and other abnormalities related to bone loss.en_US
dc.identifier.doi10.1007/s007740200050
dc.identifier.endpage349en_US
dc.identifier.issn0914-8779
dc.identifier.issue6en_US
dc.identifier.pmid12434162
dc.identifier.scopus2-s2.0-2342472848
dc.identifier.scopusqualityQ1
dc.identifier.startpage345en_US
dc.identifier.urihttps://doi.org/10.1007/s007740200050
dc.identifier.urihttps://hdl.handle.net/11468/14539
dc.identifier.volume20en_US
dc.identifier.wosWOS:000178967500005
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringer-Verlag Tokyoen_US
dc.relation.ispartofJournal of Bone and Mineral Metabolism
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAlpen_US
dc.subjectBone Mineralizationen_US
dc.subjectCreatineen_US
dc.subjectEmfen_US
dc.subjectOvariectomized Ratsen_US
dc.titleThe preventive effect on bone loss of 50-Hz, 1-mT electromagnetic field in ovariectomized ratsen_US
dc.titleThe preventive effect on bone loss of 50-Hz, 1-mT electromagnetic field in ovariectomized rats
dc.typeArticleen_US

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