The Effect of Apomorphine Therapy in the Coexistence of Parkinson's Disease and Myasthenia Gravis: A Case Report and Review of the Literature

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Tarih

2024

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Erciyes Univ Sch Medicine

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Background: The simultaneous occurrence of Parkinson's disease (PD)-a progressive neurodegenerative disorder marked by the loss of monoaminergic neurons in the substantia nigra-and Myasthenia gravis (MG)-a neuromuscular junction disease-is exceptionally rare. Although these conditions have different pathophysiological foundations, literature reports at least 29 cases of individuals diagnosed with both disorders. Case Report: We present the case of a 66-year-old patient treated for Parkinson's disease for four years before being diagnosed with MG, following the onset of dysphagia and bilateral ptosis. Apomorphine infusion, an advanced treatment option, was safely initiated. Conclusion: This case highlights the coexistence of PD and MG and illustrates the potential benefits of apomorphine infusion therapy. Apomorphine was effective in reducing symptoms, improving motor function, and enhancing the patient's quality of life.

Açıklama

Anahtar Kelimeler

Parkinson's disease, myasthenia gravis, bradykinesia, ptosis, apomorphine infusion therapy

Kaynak

Journal of Clinical Practice and Research

WoS Q Değeri

N/A

Scopus Q Değeri

Cilt

46

Sayı

3

Künye