Determination of serological profiles and avidity of specific antibodies in the sera of patients with potential Epstein-Barr virus (EBV) infection

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dc.contributor.authorAkpolat, N.
dc.contributor.authorGedik, M.
dc.contributor.authorNergiz, S.
dc.contributor.authorBilek, H.
dc.date.accessioned2024-04-24T17:24:18Z
dc.date.available2024-04-24T17:24:18Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: Epstein Barr Virus, frequently referred to as EBV, is a member of the herpesvirus family and one of the most common human viruses. The virus occurs worldwide, and most people become infected with EBV sometime during their lives. Objectives: The purpose of this study was to investigate the serological profiles of specific antibodies among the sera of suspected EBV infection patients along with VCA-IgG avidity. Methods: A total of 522 patient's sera were sent to The Clinical Microbiology Laboratory for EBV specific antibody detection and were studied by IFA method during a two year period. The serum samples were tested for EBV specific VCA IgG, VCA IgM, EA, EBNA antibodies and VCA IgG aviditity. Results: Among 33 patients those who had low avidity for VCA IgG, 27 (81.8 %) of them had a serologic profile as follows; positive VCA IgG, negative VCA IgM, negative EA and negative EBNA. Conclusion: While this profile is considered as a primary infection, the frequency of the coexistence of VCA IgG low avidity with this profile is interepreted that avidity may lead to detect primary infection (Tab. 2, Ref. 25). Full Text in PDF www.elis.sk.en_US
dc.identifier.doi10.4149/BLL_2013_096
dc.identifier.endpage463en_US
dc.identifier.issn0006-9248
dc.identifier.issn1336-0345
dc.identifier.issue8en_US
dc.identifier.pmid23944621
dc.identifier.scopus2-s2.0-84884318939
dc.identifier.scopusqualityQ2
dc.identifier.startpage460en_US
dc.identifier.urihttps://doi.org/10.4149/BLL_2013_096
dc.identifier.urihttps://hdl.handle.net/11468/19592
dc.identifier.volume114en_US
dc.identifier.wosWOS:000330269900007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherComenius Univen_US
dc.relation.ispartofBratislava Medical Journal-Bratislavske Lekarske Listy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEbv Infectionen_US
dc.subjectVca Igg Avidityen_US
dc.titleDetermination of serological profiles and avidity of specific antibodies in the sera of patients with potential Epstein-Barr virus (EBV) infectionen_US
dc.titleDetermination of serological profiles and avidity of specific antibodies in the sera of patients with potential Epstein-Barr virus (EBV) infection
dc.typeArticleen_US

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