Lethal toxicity of propafenone in a case of suicidal attempt
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Tarih
2007
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Science Bv
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Propafenone is a well-established IC class antiarrhythmic drug widely used in the treatment of a variety of supraventricular and ventricular tachyarrhythmias. Propafenone has been widely used in clinical practice in recent years. As a class IC antiarrhythmic agent it may show a significant proarrhythmogenic effect even at therapeutic doses. Toxic effects of high doses including fatal outcome have been sporadically described in the literature. Fatal course is usually associated with cardiac conduction abnormalities with progression to asystole or electromechanical dissociation. Since a specific treatment is not available and resuscitation techniques may be of limited value, early diagnosis and primary detoxication are essential. In this study, we present one case of suicidal attempt acute toxicity 7500 mg of propafenone that proceeded mortal and review the literature on this subject.
Açıklama
Anahtar Kelimeler
Intoxication, Propafenone/Overdose/Mortality
Kaynak
Turkish Journal of Emergency Medicine
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
7
Sayı
3
