Hematological disorders after renal transplantation: A single-center study
Yükleniyor...
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
İnönü Üniversitesi Tıp Fakültesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Aim: Post-transplantation anemia (PTA) and post-transplantation erythrocytosis (PTE)
are the most common hematological problems in patients after renal transplantation.
Hematological disorders need to be corrected to improve the mortality and morbidity
status of patients and to maintain cardiac and graft functions. The objective of this study
is to determine the prevalence of PTA and PTE in kidney transplant (KT) patients in our
region in our organ transplant center.
Materials and Methods: 212 renal transplant patients who underwent KT in a single
center between 2012 and 2020 were included in the study. Demographic, clinical, and
laboratory data of renal transplant patients at preoperative and postoperative months 6
and years 1, 2, 3, 4, and 5 were evaluated.
Results: We determined the prevalence of PTA to be 28.16% (Early PTA 25.62%), and
the prevalence of PTE to be 4.22%. The PTA group consisted of 40 patients, 33 females
and 7 males, with a mean age of 30.5 years, while the PTE group consisted of only 6 male
patients with a mean age of 21. Female predominance was observed in the PTA group
(33, 82.5%), and male predominance (6, 100%) was observed in the PTE group. While
there was no correlation between PTA and graft loss, there was a statistical correlation
between PTE and graft loss (p<0.001). There wasn’t relationship between the groups
in terms of mortality, tacrolimus, cyclosporin A, and erythropoietin use (p>0.05). We
found a negative correlation between hemoglobin levels and urea and a positive correlation
between albumin, Ca, and tacrolimus levels.
Conclusion: PTA is a common condition, especially in female patients, and its prevalence increases over the years if the necessary care is not taken in the follow-up, and
complications that may occur can be prevented with early diagnosis and treatment. Even
if the prevalence of PTE is low, especially young male patients should be followed, and
treatment should be started early to prevent a possible complications.
Açıklama
Anahtar Kelimeler
Kidney transplantation (KT), Post-transplantation anemia (PTA), Post-transplantation erythrocytosis (PTE), Hemoglobin
Kaynak
Annals of Medical Research
WoS Q Değeri
Scopus Q Değeri
Cilt
30
Sayı
10
Künye
Erkan, R. E. C. ve Danış, R. (2023). Hematological disorders after renal transplantation: A single-center study. Annals of Medical Research, 30(10), 1315-1322.
