Expression of sirtuin 2 and 7 in placenta accreta spectrum

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dc.authorid0000-0002-1612-0563en_US
dc.authorid0000-0001-9196-8399en_US
dc.authorid0000-0001-7982-1407en_US
dc.authorid0000-0001-5617-4067en_US
dc.authorid0000-0001-9142-6127en_US
dc.contributor.authorTaşkın, Irmak İçen
dc.contributor.authorGürbüz, Sevim
dc.contributor.authorİçen, Mehmet Sait
dc.contributor.authorDerin, Dilek Cam
dc.contributor.authorFındık, Fatih Mehmet
dc.date.accessioned2023-11-01T12:15:11Z
dc.date.available2023-11-01T12:15:11Z
dc.date.issued2023en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalıen_US
dc.description.abstractOBJECTIVE: This study aimed to investigate the expression levels of sirtuin 2 and sirtuin 7 in the placenta accreta spectrum to reveal their role in its pathogenesis. METHODS: A total of 30 placenta accreta spectrum, 20 placenta previa, and 30 controls were experienced. The sirtuin 2 and sirtuin 7 expression levels in the placentas of these groups were determined by Western blot. sirtuin 2 and sirtuin 7 serum levels in the maternal and fetal cord blood were examined by enzyme-linked immunosorbent assay. RESULTS: It was found that sirtuin 7 in placenta accreta spectrum was significantly lower in the placenta compared to the control and placenta previa groups (p[removed]0.05). CONCLUSION: Sirtuin 7 may play an important role in the formation of placenta accreta spectrum. The effect of decreased expression of sirtuin 7 might be tissue-dependent in the placenta accreta spectrum and needs to be investigated further.en_US
dc.description.sponsorshipTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) 220S416
dc.description.sponsorshipInonu University TYL-2021-2348
dc.identifier.citationTaşkın, I. İ., Gürbüz, S., İçen, M. S., Derin, D. Ç. ve Fındık, M. F. (2023). Expression of sirtuin 2 and 7 in placenta accreta spectrum. Revista da Associacao Medica Brasileira , 69(8), 1-5.en_US
dc.identifier.doi10.1590/1806-9282.20230360
dc.identifier.endpage5en_US
dc.identifier.issn1806-9282
dc.identifier.issue8en_US
dc.identifier.pmid37585995
dc.identifier.scopus2-s2.0-85168251589
dc.identifier.scopusqualityQ2
dc.identifier.startpage1en_US
dc.identifier.urihttps://www.scielo.br/j/ramb/a/4rhWT44C5YM43fTgM5BbHPz/?lang=en
dc.identifier.urihttps://hdl.handle.net/11468/13015
dc.identifier.volume69en_US
dc.identifier.wosWOS:001051569300001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorİçen, Mehmet Sait
dc.institutionauthorFındık, Fatih Mehmet
dc.language.isoenen_US
dc.publisherNLM (Medline)en_US
dc.relation.ispartofRevista da Associacao Medica Brasileira
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEpithelial-mesenchymal transitionen_US
dc.subjectPlacenta accretaen_US
dc.subjectPlacenta previaen_US
dc.subjectSirtuin 2en_US
dc.subjectSirtuinsen_US
dc.titleExpression of sirtuin 2 and 7 in placenta accreta spectrumen_US
dc.titleExpression of sirtuin 2 and 7 in placenta accreta spectrum
dc.typeArticleen_US

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