Mucosal malignant melanoma in upper aerodigestive tract: Report of two cases

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dc.contributor.authorOktay M.F.
dc.contributor.authorAskar I.
dc.contributor.authorKilinc N.
dc.contributor.authorTopcu I.
dc.date.accessioned2024-04-24T18:43:52Z
dc.date.available2024-04-24T18:43:52Z
dc.date.issued2004
dc.departmentDicle Üniversitesien_US
dc.description.abstractPrimary malignant melanoma has been seen in virtually all sites and organ systems where neural crest cells migrate. Upper aero-digestive tract is the unusual site. We presented two cases of mucosal malignant melanoma. A 59-year-old female patient had been suffering from nasal airway obstruction and headache for three months, and was admitted to our clinic. There was an upper cervical lymphadenopathy 5 cm in diameter ipsilaterally. Computerized tomography presented a nasal mass originating from the left maxillary sinus, and extending into nasal cavity and the left lateral wall of nasopharynx. Left total maxillectomy and radical neck dissection was performed. Postoperative radiotherapy was applied. A 68-year-old male patient suffering from nasal airway obstruction, hypernasality, dysphagia, and oral bleeding was admitted to our clinic. Oral examination revealed the tumoral mass protruding downward through oropharynx. The second patient referred to medical oncology. There was no recurrence in the first patient 18 months later. And the second patient died one year later. We believe that nasal mucosal malignant melanoma was rare, and carefully evaluated since it may be amelanotic lesion. Nasopharyngeal mucosal malignant melanoma is very rare, and has worse prognosis.en_US
dc.identifier.endpage18en_US
dc.identifier.issn0001-5423
dc.identifier.issue1en_US
dc.identifier.pmid15274473en_US
dc.identifier.scopus2-s2.0-2942585237en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage16en_US
dc.identifier.urihttps://hdl.handle.net/11468/24430
dc.identifier.volume46en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.relation.ispartofActa Chirurgiae Plasticaeen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMalignant Melanomaen_US
dc.subjectMaxillectomyen_US
dc.subjectNasal Cavityen_US
dc.subjectNasopharynxen_US
dc.titleMucosal malignant melanoma in upper aerodigestive tract: Report of two casesen_US
dc.typeArticleen_US

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