Association of apolipoprotein e genotype and cerebrovascular disease risk factors in a Turkish population

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Tarih

2008

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Taylor & Francis Ltd

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

The purpose of the present study was to investigate the predictive role of apolipoprotein E genotypes for stroke-related risk factors in the Turkish population. Among 100 stroke patients and 30 healthy subjects included in the study, most frequent Apo E genotype was epsilon 3/3, compatible with polymorphic distribution of Asian population. VLDL and triglyceride levels in epsilon 2/4(+) subjects were higher than in epsilon 2/4(-) patients. HDL and homocysteine levels were higher in epsilon 4/4 (+) subjects than in epsilon 4/4 (-) stroke patients. These results suggest that ApoE polymorphism in this population was not associated with any other demographic or clinical variables except for lipid profiles and homocysteine levels.

Açıklama

Anahtar Kelimeler

Apo-E Polymorphism, Hemorrhagic Stroke, Ischemic Stroke, Lipid Profile, Risk Factors, Turkish Population

Kaynak

International Journal of Neuroscience

WoS Q Değeri

Q4

Scopus Q Değeri

Q2

Cilt

118

Sayı

8

Künye