Association of apolipoprotein e genotype and cerebrovascular disease risk factors in a Turkish population
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Tarih
2008
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor & Francis Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The purpose of the present study was to investigate the predictive role of apolipoprotein E genotypes for stroke-related risk factors in the Turkish population. Among 100 stroke patients and 30 healthy subjects included in the study, most frequent Apo E genotype was epsilon 3/3, compatible with polymorphic distribution of Asian population. VLDL and triglyceride levels in epsilon 2/4(+) subjects were higher than in epsilon 2/4(-) patients. HDL and homocysteine levels were higher in epsilon 4/4 (+) subjects than in epsilon 4/4 (-) stroke patients. These results suggest that ApoE polymorphism in this population was not associated with any other demographic or clinical variables except for lipid profiles and homocysteine levels.
Açıklama
Anahtar Kelimeler
Apo-E Polymorphism, Hemorrhagic Stroke, Ischemic Stroke, Lipid Profile, Risk Factors, Turkish Population
Kaynak
International Journal of Neuroscience
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
118
Sayı
8