Çocuklarda üriner sistem infeksiyonlarında oral sefuroksim aksetil etkinliği
Yükleniyor...
Tarih
1990
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Antibiyotik ve Kemoterapi Derneği
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
İdrar yolu infeksiyonu tanısı konan 46 hastaya oral sefuroksim aksetil tedavisi uygulanmıştır. Olguların yaşı 4-13 yıl arasında olmak üzere yaş ortalaması 7.0+1.8 idi. Olguların 26'sı alt üriner sistem infeksiyonu, 14'ü pyelonefrit, 4'ü pyelonefrit+ürolitiasis ve 2'si ise kronik böbrek yetmezliği+pyelonefrit olgusuydu. Hastaların 20'sinden izole edilen E.coli, idrar kültürlerinde en sık üreyen mikroorganizma olmuştur. Tüm olgulara sefuroksim aksetil, 2x125 mg dozda, yemeklerden sonra oral yolla, on gün süreyle uygulanmış, on günlük süre sonunda klinik, biyokimyasal ve mikrobiyolojik olarak iyileşme oranı %83 olarak tespit edilmiştir. Tedavi sırasında hastaların hiçbirinde önemli bir yan etkiye rastlanmamıştır. Sonuç olarak sefuroksim aksetilin, çocuklardaki idrar yolu infeksiyonlarının tedavisinde etkili ve güvenilir bir antibiyotik olarak kullanılabileceği saptanmıştır.
Oral cefuroxime axetil treatment was administered to 46 patients diagnosed with urinary tract infection. The age of the cases was between 4-13 years and the mean age was 7.0+1.8. Twenty-six of the cases were lower urinary tract infection, 14 were pyelonephritis, 4 were pyelonephritis+urolithiasis, and 2 were chronic renal failure+pyelonephritis. E.coli isolated from 20 of the patients was the most frequently grown microorganism in urine cultures. Cefuroxime axetil was administered to all patients at a dose of 2x125 mg orally for ten days after meals, and the clinical, biochemical and microbiological recovery rate was 83% at the end of the ten-day period. No significant side effects were observed in any of the patients during the treatment. As a result, it was determined that cefuroxime axetil can be used as an effective and safe antibiotic in the treatment of urinary tract infections in children.
Oral cefuroxime axetil treatment was administered to 46 patients diagnosed with urinary tract infection. The age of the cases was between 4-13 years and the mean age was 7.0+1.8. Twenty-six of the cases were lower urinary tract infection, 14 were pyelonephritis, 4 were pyelonephritis+urolithiasis, and 2 were chronic renal failure+pyelonephritis. E.coli isolated from 20 of the patients was the most frequently grown microorganism in urine cultures. Cefuroxime axetil was administered to all patients at a dose of 2x125 mg orally for ten days after meals, and the clinical, biochemical and microbiological recovery rate was 83% at the end of the ten-day period. No significant side effects were observed in any of the patients during the treatment. As a result, it was determined that cefuroxime axetil can be used as an effective and safe antibiotic in the treatment of urinary tract infections in children.
Açıklama
Anahtar Kelimeler
Çocuk, Üriner sistem, Sefuroksim aksetil, Child, Urinary system, Cefuroxime axetil
Kaynak
Ankem Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
4
Sayı
4
Künye
Devecioğlu, C., Haspolat, Y. K. ve Donma, M. M. (1990). Çocuklarda üriner sistem infeksiyonlarında oral sefuroksim aksetil etkinliği. Ankem Dergisi, 4(4), 558-561.
