OPTIMIZATION OF ?-AMYLASE PRODUCTION BY Bacillus subtilis RSKK96: USING THE TAGUCHI EXPERIMENTAL DESIGN APPROACH

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dc.contributor.authorUysal, Ersin
dc.contributor.authorAkcan, Nurullah
dc.contributor.authorBaysal, Zubeyde
dc.contributor.authorUyar, Fikret
dc.date.accessioned2024-04-24T16:24:57Z
dc.date.available2024-04-24T16:24:57Z
dc.date.issued2011
dc.departmentDicle Üniversitesien_US
dc.description.abstractIn this study, the Taguchi experimental design was applied to optimize the conditions for alpha-amylase production by Bacillus subtilis RSKK96, which was purchased from Refik Saydam Hifzissihha Industry (RSHM). Four factors, namely, carbon source, nitrogen source, amino acid, and fermentation time, each at four levels, were selected, and an orthogonal array layout of L-16(4(5)) was performed. The model equation obtained was validated experimentally at maximum casein (1%), corn meal (1%), and glutamic acid (0.01%) concentrations with incubation time to 72 h in the presence of 1% inoculum density. Point prediction of the design showed that maximum alpha-amylase production of 503.26 U/ mg was achieved under optimal experimental conditions.en_US
dc.identifier.doi10.1080/10826068.2010.534333
dc.identifier.endpage93en_US
dc.identifier.issn1082-6068
dc.identifier.issn1532-2297
dc.identifier.issue1en_US
dc.identifier.pmid21229466
dc.identifier.scopus2-s2.0-78651389090
dc.identifier.scopusqualityQ2
dc.identifier.startpage84en_US
dc.identifier.urihttps://doi.org/10.1080/10826068.2010.534333
dc.identifier.urihttps://hdl.handle.net/11468/16908
dc.identifier.volume41en_US
dc.identifier.wosWOS:000286571800008
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofPreparative Biochemistry & Biotechnology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAlpha-Amylaseen_US
dc.subjectBacillus Subtilis Rskk96en_US
dc.subjectOptimum Conditionen_US
dc.subjectTaguchi Methodologyen_US
dc.titleOPTIMIZATION OF ?-AMYLASE PRODUCTION BY Bacillus subtilis RSKK96: USING THE TAGUCHI EXPERIMENTAL DESIGN APPROACHen_US
dc.titleOPTIMIZATION OF ?-AMYLASE PRODUCTION BY Bacillus subtilis RSKK96: USING THE TAGUCHI EXPERIMENTAL DESIGN APPROACH
dc.typeArticleen_US

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