Is urotensin 2 levels related to disease progression in acromegaly

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dc.contributor.authorEvren, Bahri
dc.contributor.authorGözel, Nevzat
dc.contributor.authorOzdemir, Fethi
dc.contributor.authorPekkolay, Zafer
dc.contributor.authorKılınç, Faruk
dc.contributor.authorCakmak, Erkan
dc.date.accessioned2024-04-24T19:13:07Z
dc.date.available2024-04-24T19:13:07Z
dc.date.issued2021
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe study aimed to compare serum Urotensin-2 stages in the patients having active acromegaly with healthy individuals and to reveal and discuss the possible effects of UII on vascular changes in acromegaly patients. In this prospective, serum urotensin stages of 30 active acromegalic patients who are followed up in the experienced adult endocrinology center were compared with the serum urotensin stages of 30 healthy volunteers. Patients' IGF-1 along with GH were carefully measured by ECLIA method, and serum urotensin stages, by ELISA method. There was no variation between two groups comparing there age (p = 0.43). Patient group, mean GH was 6.60 ng / mL with mean IGF-1 stage of 355.2 ng / mL. The mean urotensin stage was 3.62±2.27 pmol / L in the acromegaly group, 4.82±2.87 pmol / L in the healthy control group. There was no significant positive correlation of urotensin with IGF-1 stages (r = 0.11, p>0.05). Similarly, the results did not display significant positive correlation urotensin stage with GH (r = 0.13, p>0.05). Serum urotensin-2 stage was lower in acromegaly patients compared to the healthy group (control) and this variation was not statistically significant.en_US
dc.identifier.doi10.5455/medscience.2021.06.212
dc.identifier.endpage1537en_US
dc.identifier.issn2147-0634
dc.identifier.issue4en_US
dc.identifier.startpage1534en_US
dc.identifier.trdizinid504853
dc.identifier.urihttps://doi.org/10.5455/medscience.2021.06.212
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/504853
dc.identifier.urihttps://hdl.handle.net/11468/28383
dc.identifier.volume10en_US
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.relation.ispartofMedicine Science
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleIs urotensin 2 levels related to disease progression in acromegalyen_US
dc.titleIs urotensin 2 levels related to disease progression in acromegaly
dc.typeArticleen_US

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