Ultrastructural Changes in the Kidney Cortex of Rats Treated with Lead Acetate

Basit Öğe Kaydı
dc.contributor.authorDeveci, E.
dc.contributor.authorSoker, S.
dc.contributor.authorBaran, O.
dc.contributor.authorTunik, S.
dc.contributor.authorAyaz, E.
dc.contributor.authorDeveci, S.
dc.date.accessioned2024-04-24T17:24:10Z
dc.date.available2024-04-24T17:24:10Z
dc.date.issued2011
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe purpose of this study was to investigate the ultrastructural effects of lead on the kidney cortex of rats. Wistar Albino rats (180-200g body weight) were divided into a controlled and lead acetate-exposed group. Rats received lead acetate at 500 ppm in their drinking water for 60 days. Both groups were fed with the same standard food, but lead acetate was added to the drinking water. During the experimental period, blood samples were taken from the abdominal aorta of the anesthetised animals. At the end of exposure, body weight and blood lead levels were measured. The kidney tissue samples were prepared and analyzed by light and transmission electron microscopy. Cortical renal tubules show various degenerative changes with focal tubular necrosis invaded by inflammatory cells. The ultrastructural alterations found in lead acetate-treated rats were a diminution in the amount of filtration slits, increased fusion of foot processes in epithelial cells of the glomeruli, increase of lysosomal structures and pinocytic vesicles as well as large mitochondria in proximal tubule cells.en_US
dc.identifier.doi10.4067/S0717-95022011000300067
dc.identifier.endpage1061en_US
dc.identifier.issn0717-9502
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-80155181227
dc.identifier.scopusqualityQ3
dc.identifier.startpage1058en_US
dc.identifier.urihttps://doi.org/10.4067/S0717-95022011000300067
dc.identifier.urihttps://hdl.handle.net/11468/19477
dc.identifier.volume29en_US
dc.identifier.wosWOS:000299647600067
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherSoc Chilena Anatomiaen_US
dc.relation.ispartofInternational Journal of Morphology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectLead Acetateen_US
dc.subjectKidney Cortexen_US
dc.subjectUltrastructural Changesen_US
dc.titleUltrastructural Changes in the Kidney Cortex of Rats Treated with Lead Acetateen_US
dc.titleUltrastructural Changes in the Kidney Cortex of Rats Treated with Lead Acetate
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu