Phenolic compounds, antioxidant and antibacterial activities of cedrus Atlantica stem barks

Basit Öğe Kaydı
dc.authorid0000-0002-4090-7227
dc.authorid0000-0001-8932-4535
dc.authorid0000-0002-2193-8386
dc.contributor.authorBenmerache, Abbes
dc.contributor.authorKabouche, Ahmed
dc.contributor.authorKabouche, Zahia
dc.contributor.authorÖztürk, Mehmet
dc.contributor.authorÇakır, Cansel
dc.contributor.authorYılmaz, Mustafa Abdullah
dc.contributor.authorErtaş, Abdulselam
dc.date.accessioned2025-02-22T14:09:06Z
dc.date.available2025-02-22T14:09:06Z
dc.date.issued2024
dc.departmentDicle Üniversitesi, Eczacılık Fakültesi, Temel Eczacılık Bilimleri Bölümüen_US
dc.description.abstractStem barks of Cedrus atlantica were investigated for their antioxidant and antibacterial activities and their chemical composition. The phenolic ingredients of the extracts were studied using LC-MS/MS against twenty-seven phenolic compounds. The antioxidant activity was evaluated by DPPH, O-2-DMSO-alkaline, ABTS, beta-carotene-linoleic acid and CUPRAC assays, while the antibacterial activity was performed using the disk diffusion and MIC assays. In addition, the phenolic and flavonoid contents were determined as gallic acid and quercetin equivalents, respectively. Ethyl acetate extract exhibited the highest activity in DPPH, O-2-DMSO alkaline, ABTS, beta-carotene linoleic acid and CUPRAC assays (IC50 = 10.85 +/- 1.41, 3.36 +/- 0.40, 0.74 +/- 0.03, 10.03 +/- 0.01, A(0.50) = 23.56 +/- 1.67 mu g/mL, respectively), followed by n-butanol and hydromethanol extracts. In addition, the ethyl acetate and n-butanol extracts showed remarkable antibacterial activity against Enterobacter aerogenes and Staphylococcus aureus (ATCC 43300), respectively. The LC-MS/MS analyses of all extracts afforded high amounts of quinic acid, malic acid, rosmarinic acid, protocatechuic acid, chlorogenic acid, coumarin, vanillin, and quercetin, exhibiting antioxidant activity.en_US
dc.description.sponsorshipDGRSDT-MESRS (Algeria); Mugla Sytky Kocman University, Research Projects Coordination Office [17/216]en_US
dc.description.sponsorshipThe authors are grateful to DGRSDT-MESRS (Algeria) and Mugla Sytky Kocman University, Research Projects Coordination Office for financial support (project No. 17/216).en_US
dc.identifier.citationBenmerache, A., Kabouche, A., Kabouche, Z., Öztürk, M., Çakır, C., Yılmaz, M. A. ve diğerleri. (2024). Phenolic compounds, antioxidant and antibacterial activities of cedrus Atlantica stem barks. Pharmaceutical Chemistry Journal, 58(6), 943-949.
dc.identifier.doi10.1007/s11094-024-03227-6
dc.identifier.endpage949en_US
dc.identifier.issn0091-150X
dc.identifier.issn1573-9031
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-85206997412en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage943en_US
dc.identifier.urihttps://doi.org/10.1007/s11094-024-03227-6
dc.identifier.urihttps://hdl.handle.net/11468/29791
dc.identifier.volume58en_US
dc.identifier.wosWOS:001339235200002
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorYılmaz, Mustafa Abdullah
dc.institutionauthorErtaş, Abdulselam
dc.institutionauthorid0000-0002-4090-7227
dc.institutionauthorid0000-0002-2193-8386
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofPharmaceutical Chemistry Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKA_WOS_20250222
dc.subjectCedrus atlanticaen_US
dc.subjectAntibacterial activityen_US
dc.subjectAntioxidant activityen_US
dc.subjectPhenolic compoundsen_US
dc.titlePhenolic compounds, antioxidant and antibacterial activities of cedrus Atlantica stem barksen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
Phenolic Compounds, Antioxidant and Antibacterial Activities of Cedrus Atlantica Stem Barks.pdf
Boyut:
98.94 KB
Biçim:
Adobe Portable Document Format
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Eczacılık Fakültesi Temel Eczacılık Bilimleri Bölümü Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu