Adjuvant chemoradiotherapy for cancer of the rectum: Postoperative or preoperative?
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Tarih
2006
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Cancer of the rectum is a frequent malign disease of both sexes and its primary treatment is surgery. Postoperative chemotherapy is the generally preferred adjuvant treatment modality but its results are not still satisfactory. Recent studies have reported that total mesorectal excision technique with preoperative chemoradiotherapy is superior to postoperative adjuvant treatment in terms of local disease control. The question of timing of the adjuvant treatments like radiotherapy, chemotherapy and chemoradiotherapy will be discussed in light of the randomized clinical trials with sufficient patient number. In conclusion, current recommendation is preoperative concomitant chemotherapy plus radiotherapy.
Açıklama
Anahtar Kelimeler
Antineoplastic Combined Chemotherapy Protocols, Neoadjuvant Therapy, Rectal Neoplasm
Kaynak
UHOD - Uluslararasi Hematoloji-Onkoloji Dergisi
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
16
Sayı
1
