Age-related changes in the expression of ICAM-1 in the aorta of wistar albino rats

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dc.contributor.authorKetani, Sennur
dc.contributor.authorKarakoç, Zelal
dc.contributor.authorKetani, M. Aydın
dc.contributor.authorKılınç, Mehmet
dc.date.accessioned2024-04-24T17:24:11Z
dc.date.available2024-04-24T17:24:11Z
dc.date.issued2016
dc.departmentDicle Üniversitesi, Ziya Gökalp Eğitim Fakültesi, Matematik ve Fen Bilimleri Eğitimi Bölümüen_US
dc.description.abstractICAM-1 which is expressed by endothelial cells and leukocytes are observed as first markers in diseases such as transplant rejection, diabetes and atherosclerosis and in infections caused by various pathogens. In the present study, it is aimed to reveal the age-related changes in the expression of ICAM-1 on rats. Therefore, a total of 30 albino rats were taken at the age of 6, 18 and 24 months without gender discrimination. Rats were fed with standard pellet feed during the study. Afterwards, rats were sacrificed and tissue samples were collected from their rats, and the samples were evaluated under the light microscope by staining with immnunohistochemical method. It was determined that the expression of both aortic endothelial cells and endothelial cells in the media layer had been significantly increased based on the age.en_US
dc.identifier.citationKetani, Ş., Karakoç, Z., Ketani, M. A. ve Kılınç, M. (2016). Age-related changes in the expression of ICAM-1 in the aorta of wistar albino rats. International Journal of Morphology, 34(4), 1482-1486.
dc.identifier.doi10.4067/S0717-95022016000400049
dc.identifier.endpage1486en_US
dc.identifier.issn0717-9502
dc.identifier.issn0717-9367
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85011347384
dc.identifier.scopusqualityQ3
dc.identifier.startpage1482en_US
dc.identifier.urihttps://doi.org/10.4067/S0717-95022016000400049
dc.identifier.urihttps://hdl.handle.net/11468/19495
dc.identifier.volume34en_US
dc.identifier.wosWOS:000395669600049
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherSoc Chilena Anatomiaen_US
dc.relation.ispartofInternational Journal of Morphology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectIcam-1en_US
dc.subjectRaten_US
dc.subjectAortic Endotheliumen_US
dc.subjectAgeen_US
dc.titleAge-related changes in the expression of ICAM-1 in the aorta of wistar albino ratsen_US
dc.titleAge-related changes in the expression of ICAM-1 in the aorta of wistar albino rats
dc.typeArticleen_US

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