Patient characteristics and management practices in chronic myeloid leukemia in Turkey: reflections from an expert meeting
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Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor & Francis
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Introduction The therapeutic landscape of chronic myeloid leukemia (CML) has evolved significantly since the introduction of imatinib. The European LeukemiaNet (ELN) recommendations serve as a guide for diagnosis, treatment, and monitorization of CML, but availability and accessibility of diagnostic tools and medications affect their applicability. Areas covered This article provides an overview of the current clinical management of CML in Turkey with reference to the key outputs of the online expert meeting held in November 2020. The applicability of the ELN 2020 recommendations for treating CML in clinical practice was also discussed. Expert opinion Imatinib is the only reimbursed and the most preferred first-line treatment in CML restricting the upfront use of second-generation tyrosine kinase inhibitors (TKIs), thereby limiting the applicability of treatment-free remission approach in Turkey. The ELN recommendations about using the EUTOS Long-Term Survival (ELTS) score for risk assessment and focusing on patient reported outcomes and quality of life can be enhanced with educational activities. The widespread availability of standardized technical infrastructure for diagnosing and monitoring CML will contribute to better disease management. Establishing a sustainable national database for CML is valuable for observing patient characteristics and disease outcomes as well as the impact of treatment patterns over time.
Açıklama
WOS:000764920100001
PMID: 35184657
PMID: 35184657
Anahtar Kelimeler
Chronic myeloid leukemia, CML, Comorbidities, Risk scoring, TKI, Tyrosine kinase inhibitor, TFR, Treatment-free remission
Kaynak
Expert Review of Hematology
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
Early Access
Sayı
Künye
Eşkazan, A.E., Ali, R., Alnıgeniş, E., Ayyıldız, O., Haznedaroğlu, İ., Kırkızlar, O. ve diğerleri. (2022). Patient characteristics and management practices in chronic myeloid leukemia in Turkey: reflections from an expert meeting. Expert Review of Hematology, Early Access.
