Akut viral hepatit A olguların klinik ve laboratuar bulgularının değerlendirilmesi
Yükleniyor...
Tarih
2008
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Dicle Üniversitesi Tıp Fakültesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Attribution-NonCommercial 3.0 United States
Attribution-NonCommercial 3.0 United States
Özet
Akut viral hepatit A enfeksiyonu genellikle asemptomatik ve anikterik
seyirli olup, daha çok çocukluk yaş grubunda görülmektedir. Bu çalışmada
Ocak 2006 ile Şubat 2007 tarihleri arasında Dicle Üniversitesi Tıp Fakültesi
Çocuk Sağlığı ve Hastalıkları Anabilim Dalı Enfeksiyon Hastalıkları
Kliniğinde yatırılan 42 akut viral hepatit A enfeksiyonlu hastanın dosyaları
retrospektif olarak incelendi. Hastaların yaş ortalaması 6.9±3.5 yıl (18 ay14 yaş), erkek kız oranı 1.4 bulundu. En sık başvuru şikayetleri sarılık
(%73.8), kusma (%52.3), ateş (%42.8), karın ağrısı (%38.1) iken başvuru
mevsimi kış (%47.6), sonbahar (%38.1) ve ilkbahar (%14.3) idi. Laboratuar
bulgularında ortalama aspartat aminotransferaz (AST) 1875U/L (82-
6340U/L), alanin aminotransferaz (ALT) 1697U/L (144-4876 U/L), total
bilirubin 12.1mg/dl (0.9-47mg/dl) ve direkt bilirubin 8.9mg/dl (0.4-27.3
mg/dl) olarak saptandı. En sık görülen komplikasyonlar anemi, hepatik
ensefalopati ve trombositopeni idi. Mortalite oranı %2.4 olarak belirlendi.
Acute viral hepatitis A is usually, which asymptomatic and anicteric, has often been seen in children. In this study, the files of 42 patients with acute viral hepatitis A infection who were admitted at the Department of Pediatrics, Medical Faculty, Dicle University, between January 2006 and February 2007, were evaluated retrospectively. Male/female rate was determined to be 1.4, and the mean ages of patients were 6.9±3.5 years (18months to14 years). The most common symptoms on admission were jaundice (73.8%), vomiting (52.3%), fever (42.8%) and abdominal pain (38%). The seasons on admission were winter (47.6%), autumn (38.1%) and spring (14.3%). In laboratory findings mean of aspartate aminotransferase (AST) 1875U/L (82-6340U/L), alanine aminotransferase (ALT) 1697U/L (144-4876 U/L), total bilirubin 12.1mg/dl (0.9-47mg/dl), and direct bilirubin 8.9mg/dl (0.4-27.3 mg/dl) were determined. The most frequent complications were anemia, hepatic encephalopathy, thrombocytopenia, and the mortality rate was determined as 2.4%.
Acute viral hepatitis A is usually, which asymptomatic and anicteric, has often been seen in children. In this study, the files of 42 patients with acute viral hepatitis A infection who were admitted at the Department of Pediatrics, Medical Faculty, Dicle University, between January 2006 and February 2007, were evaluated retrospectively. Male/female rate was determined to be 1.4, and the mean ages of patients were 6.9±3.5 years (18months to14 years). The most common symptoms on admission were jaundice (73.8%), vomiting (52.3%), fever (42.8%) and abdominal pain (38%). The seasons on admission were winter (47.6%), autumn (38.1%) and spring (14.3%). In laboratory findings mean of aspartate aminotransferase (AST) 1875U/L (82-6340U/L), alanine aminotransferase (ALT) 1697U/L (144-4876 U/L), total bilirubin 12.1mg/dl (0.9-47mg/dl), and direct bilirubin 8.9mg/dl (0.4-27.3 mg/dl) were determined. The most frequent complications were anemia, hepatic encephalopathy, thrombocytopenia, and the mortality rate was determined as 2.4%.
Açıklama
Anahtar Kelimeler
Akut viral hepatit A, Çocuk, Klinik ve laboratuar bulguları, Acute viral hepatitis A, Child, Clinical and laboratory findings
Kaynak
Dicle Tıp Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
35
Sayı
3
Künye
Taşkesen, M., Taş, M.A., Ecer, S., Özel, A.K. ve Karabiberoğlu, S. (2008). Akut viral hepatit A olguların klinik ve laboratuar bulgularının değerlendirilmesi. Dicle Tıp Dergisi, 35(3), 155-158.
