Diagnostic value of screening tests in subgroups of women with recurrent pregnancy loss
[ X ]
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Taylor & Francis Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: To evaluate the diagnostic value of screening laboratory tests in women who had recurrent pregnancy loss (RPL). Methods: A total of 252 women with RPL managed in our tertiary referral research and education hospital were included in the study. Risk factors recorded involved age, gravidity, parity, number of prior live births, number of pregnancy losses, and thrombophlia tests. The cases were divided into three different groups and each group was analyzed separately. Results: There was no statistically significant difference between the first and second groups in terms of clinical and laboratory parameters (p>0.05). In the third group, there was a statistically significant difference among cases in terms of parity, gravidity, number of pregnancy losses, serum AT III levels, APCR, and age of the women. According to the logistic regression model, odds ratios (95% CI) were 6.116 (3.797-9.852), 5.665 (2.657-12.079), 4.763 (3.099-7.321), 4.729 (3.080-7.260), 2.820 (1.836-4.333), and 1.911 (1.232-2.965), respectively. Conclusions: We do not recommend the screening of all women with RPL, but in women with high parity and those who had prior live birth pregnancies, increased AT III, and APCR may be diagnostic markers for subsequent pregnancy loss.
Açıklama
Anahtar Kelimeler
Diagnostic Value, Recurrent Pregnancy Loss, Screening Tests, Subgroup
Kaynak
Journal of Maternal-Fetal & Neonatal Medicine
WoS Q Değeri
Q3
Scopus Q Değeri
Q1
Cilt
28
Sayı
4
