Phytochemical analysis of essential oils and the extracts of an ethnomedicinal plant, Teucrium multicaule collected from two different locations with focus on their important biological activities
Yükleniyor...
Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Teucrium species have been among the most commonly used traditional medicinal plants and they are
known to have extensive therapeutic applications. The main focus of this study, Teucrium multicaule is also
renowned for being an important medicinal and aromatic plant in Turkiye. Volatile profiling of the essential
oils was conducted by GC MS, phytochemical profiling of the ethanol extracts was carried out by LC HRMS,
antioxidant, anticholinesterase, antityrosinase, antiurease, antidiabetic, anticancer, and antimicrobial activities were revealed by different assays. Germacrene D was the most abundant compound in the essential oils
from Diyarbakir (TmuD) with 45.4%, and Batman (TmuB) with 54.7%. All extracts were found to be quite rich
in phytochemicals by LC HRMS, and herniarin, caffeic acid, naringenin, luteolin, scutellarein, hispidulin,
rhamnocitrin, penduletin, eupatilin, (-)-epigallocatechin gallate, hederagenin, and verbascoside were found
to be present in all extracts. T. multicaule roots extract from Diyarbakir (TmuRD) demonstrated the highest
radical scavenging, a-amylase inhibitory (59.82§0.36%), and antibutyrylcholinesterase activity (61.96§
1.72%), whereas T. multicaule aerial parts extract from Batman (TmuHB) exhibited the strongest antityrosinase (66.17§0.92%), antiurease (67.85§0.69%), and cytotoxic (54.76 § 1.57 mg/mL) activities. TmuRD also
showed significant antimicrobial activity against S. epidermidis with 156.2 mg/mL MIC value. As revealed by
this first detailed report on T. multicaule, the plant demonstrates various important biological activities
attributed to its rich phytochemicals, which also justifies its use in ethnomedicine.
Açıklama
Anahtar Kelimeler
Teucrium multicaule, LC-HRMS, Enzyme inhibitory activity, Cytotoxicity, Traditional uses
Kaynak
South African Journal of Botany
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
Sayı
153
Künye
Ersoy, E., Tanaman, I., Özkan, E. E., Karahan, S., Şahin, H., Çınar, E. ve diğerleri. (2023). Phytochemical analysis of essential oils and the extracts of an ethnomedicinal plant, Teucrium multicaule collected from two different locations with focus on their important biological activities. South African Journal of Botany, (153), 124-135.
