Dicle Üniversitesinde yatan çocuk COVID-19 hastalarının, klinik, laboratuvar ve demografik özelliklerinin değerlendirilmesi
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Tarih
2022
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Dicle Üniversitesi, Tıp Fakültesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Giriş ve Amaç: Bu çalışma; Dicle Üniversitesi Tıp Fakültesi Çocuk Hastanesine Mart 2020-Kasım 2021 yılları arasında COVID-19 tanısı almış hastaların Radyolojik görüntüleme, Laboratuvar ve Klinik takiplerinin değerlendirilmesi amaçlandı. Gereç ve Yöntem: Hastanemize COVID-19 tanısı alan 0-16 yaş arasında 220 hastanın yatış, klinik, laboratuar ve demografik özellikleri retrospektif olarak incelendi. Bulgular: Hastaların %57,3'ünün erkek, %42,7'sinin kız olduğu, ortalama yaşlarının 107,8±65,5 (min. 1- max. 192) ay olduğu saptandı. Hastalığı asemptomatik geçirenler %48,6 (n=107), hafif geçiren hastalar %35,5 (n=78), orta şiddette geçirenler %11,8 (n=26) ve ağır şiddette geçirenler %3,6 (n=8) oluşturmaktaydı. PAAC grafisi çekilen 220 hastadan 13'ünde (%12) COVID-19 ile ilişkili bir akciğer bulgusu saptandı. En sık gözlenen bulgular sırasıyla Bilateral buzlu cam görüntüsü (n=5; %2,3), Bilateral buzlu cam / konsolidasyon (n=4; %1,8) ve Uniteral buzlu cam (n=2; %1) idi. Hastaların 43'üne bilgisayarlı akciğer tomografisi çekildi. Bu hastaların 16'inde (%7,7) COVID-19 ile ilişkili bir akciğer bulgusu mevcudiyeti saptandı. Sırasıyla en sık saptanan üç bulgu Bilateral buzlu cam görünümü (n=5; %2,4), Konsolidasyon artışı (n=4; %1,9) ve atelektazi (n=3; %1,4) idi. PAAC grafisinde görüntüleme bulgusu olanların daha çok pediatrik yoğun bakım ihtiyacı olduğu, yatış sürelerinin daha uzun olduğu, komorbidit hastalık varlığı, öksürük, takipne şikayetlerinin daha belirgin olduğu ve Akut faz reaktanlarının (Ferritin, Fibrinojen, Laktat dehidrogenaz (LDH), C-Reaktif protein (CRP)) daha yüksek olduğu saptandı (p<0,05). Hastaların yatış yerleri ile ALC, CRP, LDH, ALT, AST, Ferritin, Fibronojen, D-Dimer ve Yatış Süreleri arasında istatistiksel olarak anlamlı bir fark olduğu görüldü (p< 0,001). Hastaların Laboratuvar sonuçlarına göre D-vitamini ile WBC, ANC, ALC, CRP, Fibronojen, Ferritin, LDH, PLT, Hb, Troponin, CK, Glikoz ve Kreatin arasında istatistiksel olarak anlamlı bir fark olduğu saptandı (p< 0,001). Sonuç: Hastalık şiddeti arttıkça radyolojik bulguların arttığı, 1 yaş altı çocuklarda görüntüleme bulgularının diğer yaş gruplarına göre daha fazla olduğu görülmüştür. Bu sonuçlar eşliğinde COVID-19 süphesi olan çocuklarda görüntüleme yöntemlerinin II gerekli durumlarda yapılıp, hastalığın seyri ve şiddeti hakkında önbilgi verebileceğini düşünüyoruz.
Introduction and Objective: This study aims to evaluate the Radiological imaging, Laboratory findings, and Clinical follow-up of patients diagnosed with COVID-19 at Dicle University Faculty of Medicine Children's Hospital between March 2020 and November 2021. Material and Method: The hospitalization, clinical, laboratory, and demographic characteristics of 220 patients in the 0-16 age group, who were diagnosed with COVID-19 in our hospital, were retrospectively analyzed. Results: Of the patients, 57.3% were male, 42.7% were female, and the mean age was 107.8±65.5 (min.1-max.192) months. The asymptomatic patients accounted for 48.6% (n=107), those with mild disease accounted for 35.5% (n=78), those with moderate severity were 11.8% (n=26), and those with severe disease accounted for 3.6% (n=8). Of the 220 patients who underwent posteroanterior (PA) chest X-ray, 13 (12%) had a pulmonary finding associated with COVID-19. The most common findings were Bilateral ground-glass opacity (n=5, 2.3%), Bilateral ground-glass / consolidation (n=4, 1.8%), and Uniteral ground-glass opacity (n=2, 1%), respectively. CT pulmonary angiography was taken in 43 of the patients. Of these patients, 16 (7.7%) had a COVID-19-related pulmonary finding. The three most common findings were bilateral ground-glass opacity (n=5, 2.4%), increased consolidation (n=4, 1.9%), and atelectasis (n=3, 1.4%), respectively. Those with imaging findings in their PA chest X-ray were found to need more pediatric intensive care, had longer duration of hospitalization, had a comorbid disease, cough, pronounced tachypnea complaints, and higher Acute phase reactants (Ferritin, Fibrinogen, Lactate dehydrogenase (LDH), C- Reactive protein (CRP)) (p<0.05). There was a statistically significant difference between the hospitalization units of the patients and their ALC, CRP, LDH, ALT, AST, Ferritin, Fibronogen, D-Dimer and Length of hospital stay (p<0.001). According to the laboratory results of the patients, there was a statistically significant difference between vitamin D and WBC, ANC, ALC, CRP, Fibronogen, Ferritin, LDH, PLT, Hb, Troponin, CK, Glucose, and Creatine levels (p<0.001). IV Conclusion: It was observed that radiological findings increase as the severity of the disease increases, and imaging findings were more common in children under the age of 1 than in other age groups. In the light of these results, we believe that imaging methods can be performed when necessary in children with suspected COVID-19 to have preliminary information about the course and severity of the disease.
Introduction and Objective: This study aims to evaluate the Radiological imaging, Laboratory findings, and Clinical follow-up of patients diagnosed with COVID-19 at Dicle University Faculty of Medicine Children's Hospital between March 2020 and November 2021. Material and Method: The hospitalization, clinical, laboratory, and demographic characteristics of 220 patients in the 0-16 age group, who were diagnosed with COVID-19 in our hospital, were retrospectively analyzed. Results: Of the patients, 57.3% were male, 42.7% were female, and the mean age was 107.8±65.5 (min.1-max.192) months. The asymptomatic patients accounted for 48.6% (n=107), those with mild disease accounted for 35.5% (n=78), those with moderate severity were 11.8% (n=26), and those with severe disease accounted for 3.6% (n=8). Of the 220 patients who underwent posteroanterior (PA) chest X-ray, 13 (12%) had a pulmonary finding associated with COVID-19. The most common findings were Bilateral ground-glass opacity (n=5, 2.3%), Bilateral ground-glass / consolidation (n=4, 1.8%), and Uniteral ground-glass opacity (n=2, 1%), respectively. CT pulmonary angiography was taken in 43 of the patients. Of these patients, 16 (7.7%) had a COVID-19-related pulmonary finding. The three most common findings were bilateral ground-glass opacity (n=5, 2.4%), increased consolidation (n=4, 1.9%), and atelectasis (n=3, 1.4%), respectively. Those with imaging findings in their PA chest X-ray were found to need more pediatric intensive care, had longer duration of hospitalization, had a comorbid disease, cough, pronounced tachypnea complaints, and higher Acute phase reactants (Ferritin, Fibrinogen, Lactate dehydrogenase (LDH), C- Reactive protein (CRP)) (p<0.05). There was a statistically significant difference between the hospitalization units of the patients and their ALC, CRP, LDH, ALT, AST, Ferritin, Fibronogen, D-Dimer and Length of hospital stay (p<0.001). According to the laboratory results of the patients, there was a statistically significant difference between vitamin D and WBC, ANC, ALC, CRP, Fibronogen, Ferritin, LDH, PLT, Hb, Troponin, CK, Glucose, and Creatine levels (p<0.001). IV Conclusion: It was observed that radiological findings increase as the severity of the disease increases, and imaging findings were more common in children under the age of 1 than in other age groups. In the light of these results, we believe that imaging methods can be performed when necessary in children with suspected COVID-19 to have preliminary information about the course and severity of the disease.
Açıklama
Anahtar Kelimeler
COVID-19, Çocuk yoğun bakım ünitesi, Klinik, Laboratuvar, Pediatric intensive care unit, Clinic, Laboratory
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Künye
Akay, C. (2022). Dicle Üniversitesinde yatan çocuk COVID-19 hastalarının, klinik, laboratuvar ve demografik özelliklerinin değerlendirilmesi. Yayımlanmamış uzmanlık tezi, Dicle Üniversitesi, Diyarbakır.
