Effects of Xylene on Respiratory Mucosa in Rats
[ X ]
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Soc Chilena Anatomia
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study we examined the effects histopathologic and immunohistochemical of xylene inhalation in rats by using light microscopy. Adult wistar albino rats were used in this study. Eight rats were in control group and 8 rats were in the experimental group. The experimental group was exposed to 300 ppm formaldehyde 3-5 min/day, 5 days/week for 8 weeks. The lining epithelium of respiratory mucosa showed a loss of ciliated cells with metaplasia of goblet cells, hyperplasia of squamous cells and edema, inflamation in sub epithelial area). In the group treated xylene. Disruption of cell-cell contact was observed. Weak expression of E-cadherin was observed between cells. The vascular endothelium of capillaries and venoles showed intense immunostaining for VEGF.
Açıklama
Anahtar Kelimeler
Xylene, Vascular Endothelial Growth Factor, E-Cadherin, Respiratory Mucosa
Kaynak
International Journal of Morphology
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
34
Sayı
3
