A molecularly imprinted nanofilm-based quartz crystal microbalance sensor for the real-time detection of pirimicarb

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Küçük Resim

Tarih

2019

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Wiley

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

This study aimed to prepare a novel quartz crystal microbalance (QCM) sensor for the detection of pirimicarb. Pirimicarb-imprinted poly (ethylene glycol dimethacrylate-N-metacryloyl-(l)-tryptophan methyl ester) [p (EGDMA-MATrp)] nanofilm (MIP) on the gold surface of a QCM chip was synthesized using the molecular imprinting technique. A nonimprinted p (EGDMA-MATrp) nanofilm (NIP) was also synthesized using the same experimental technique. The MIP and NIP nanofilms were characterized via Fourier transform infrared spectroscopy attenuated total reflectance spectroscopy, contact angle, atomic force microscopy, and an ellipsometer. A competitive adsorption experiment on the sensor was performed to display the selectivity of the nanofilm. An analysis of the QCM sensor showed that the MIP nanofilm exhibited high sensitivity and selectivity for pirimicarb determination. A liquid chromatography-tandem mass spectrometry method was prepared and validated to determine the accuracy and precision of the QCM sensor. The accuracy and precision of both methods were determined by a comparison of six replicates at three different concentrations to tomato samples extracted by using a Quick, Easy, Cheap, Effective, Rugged and Safe (QuEChERS) method. The limit of detection of the QCM sensor was found to be 0.028 nM. In conclusion, the QCM sensor showed good accuracy, with recovery percentages between 91 and 94%. Also, the pirimicarb-imprinted QCM sensor exhibited a fast response time, reusability, high selectivity and sensitivity, and a low limit of detection. Therefore, it offers a serious alternative to the traditional analytical methods for pesticide detection in both natural sources and aqueous solutions.

Açıklama

Anahtar Kelimeler

Lc-Ms, Ms, Molecularly imprinted polymers, Pirimicarb, Quartz crystal microbalance, Sensor

Kaynak

Journal of Molecular Recognition

WoS Q Değeri

Q3

Scopus Q Değeri

Q3

Cilt

32

Sayı

9

Künye

Çakır, O. (2019). A molecularly imprinted nanofilm-based quartz crystal microbalance sensor for the real-time detection of pirimicarb. Journal of Molecular Recognition, 32(9), 1-10.