Comparison of epidural administration of bupivacaine-fentanyl, bupivacaine-morphine and bupivacaine-fentanyl morphine combinations
[ X ]
Tarih
1994
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Addition of fentanyl, morphine or fentanyl and morphine to bupivacaine administered for epidural anaesthesia was evaluated in eighty healthy patients. The patients were randomized into four equal groups to receive epidural anaesthesia in a double blind design, 20 ml of 0.5% bupivacaine (group 1), 20 ml of 0.5% bupivacaine with 75 ?g fentanyl (group 2), 20 ml of 0.5% bupivacaine with 30 ?g fentanyl and 1.5 mg morphine (group 3) and 20 ml of 0.5% bupivacaine with 3 mg morphine (group 4). The times for sensory block to develop bilaterally to T12, the time to achieve maximal sensory block, time to request postoperative analgesia and side effects were assessed. The onset time of sensory anaesthesia to T12 was significantly shorter in groups 2 and 3 (4.4 ± 1.2 and 4.1 ± 1 min. vs 6.8 ± 1.8 min. in group 1 and 6.25 ± 1.2 min, in group 4). There mere no significant differences in the, time to achieve maximal sensory block in any group. Duration of analgesia assessed during postoperative period was significantly longer in groups 3 and 4 (1209 ± 860 min. in group 3, 1224 ± 854 min. in group 4 vs 290.1 ± 60 min. in group 1 and 471.1 ± 96 min. in group 2). A decrease in mean arterial pressure of more than 30% of baseline values as observed 10-15% in each group.
Açıklama
Anahtar Kelimeler
Anaesthetic Techniques, Bupivacaine, Epidural, Fentanyl, Local Anaestetics, Morphine
Kaynak
Acta Anaesthesiologica Italica
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
45
Sayı
4
