Protective Role of Vitamin C on Sperm Characteristics and Testicular Damage in Rats Exposed to Radiation

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dc.contributor.authorTas, Muzaffer
dc.contributor.authorCirit, Umut
dc.contributor.authorOzkan, Oktay
dc.contributor.authorDenli, Muzaffer
dc.contributor.authorZincircioglu, Seyit Burhanedtin
dc.contributor.authorSeker, Ugur
dc.contributor.authorOzmen, Mehmet Ferit
dc.date.accessioned2024-04-24T17:33:09Z
dc.date.available2024-04-24T17:33:09Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe aim of this study was to investigate the protective effects of vitamin C on sperm characteristics and testes in male rats exposed gamma radiation (2 Gy). A total of 21 adult male wistar albino rats (8 weeks of age, weighing 180-220 g) were divided into three groups. Control, radiotherapy (received scrotal.-radiation of 2 Gy as a single dose) and radiotherapy + vitamin C treated rats (during the 55 days after irradiation, 500 mg vitamin C/500 ml water daily orally). Testes samples from all groups were taken at day 55 post-irradiation and epididymal sperm characteristics, all-genital organs weights and testes histology were evaluated. Radiotherapy decreased significantly the sperm motility, concentration, left testes and epididymis weights, Johnsen's biopsy score and seminiferous tubular diameter but it increased the sperm head defects as compared to the Control group (P<0.05). The administration of vitamin C only reduced the harmful effects of radiotherapy on the seminiferous tubular diameter (P<0.05). It has been concluded that the radiotherapy may cause alteration in the genital organ weights, spermatologic and hystologic parameters in rats and administration of vitamin C may be slightly beneficial for seminiferous tubular diameter following testicular irradiation during the radiotherapy.en_US
dc.identifier.doi10.9775/kvfd.2013.9445
dc.identifier.endpage64en_US
dc.identifier.issn1300-6045
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-84887269924
dc.identifier.scopusqualityQ3
dc.identifier.startpage59en_US
dc.identifier.trdizinid153837
dc.identifier.urihttps://doi.org/10.9775/kvfd.2013.9445
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/153837
dc.identifier.urihttps://hdl.handle.net/11468/20478
dc.identifier.volume20en_US
dc.identifier.wosWOS:000328083200009
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.publisherKafkas Univ, Veteriner Fakultesi Dergisien_US
dc.relation.ispartofKafkas Universitesi Veteriner Fakultesi Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRadiationen_US
dc.subjectVitamin Cen_US
dc.subjectSpermen_US
dc.subjectTestesen_US
dc.subjectRaten_US
dc.titleProtective Role of Vitamin C on Sperm Characteristics and Testicular Damage in Rats Exposed to Radiationen_US
dc.titleProtective Role of Vitamin C on Sperm Characteristics and Testicular Damage in Rats Exposed to Radiation
dc.typeArticleen_US

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