Oxidative stress parameters and ceruloplasmin levels in patients with severe preeclampsia

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dc.contributor.authorDemir, M. E.
dc.contributor.authorUlas, T.
dc.contributor.authorDal, M. S.
dc.contributor.authorEren, M. A.
dc.contributor.authorAydogan, H.
dc.contributor.authorYalcin, S.
dc.contributor.authorCamuzcuoglu, A.
dc.date.accessioned2024-04-24T17:28:20Z
dc.date.available2024-04-24T17:28:20Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground. Oxidative stress is believed to have a role in the development of preeclampsia (PE). It is known that an increased ceruloplasmin (CP) level is also associated with PE. The aim of this study was to investigate the relationship between oxidative stress parameters and CP levels in patients with severe PE. Patients and Methods. Sixty patients with severe PE and 60 healthy pregnant women were recruited to the study. All study subjects were divided into 2 groups; group 1(n=60) consisted of patients with severe PE, and group 2 (n=60) consisted of healthy pregnant subjects. Blood samples were obtained to measure CP, total antioxidant status and total oxidant status from all subjects. Oxidative stress index was calculated. Results. Compared to group 2; group 1 had significantly higher CP, total oxidant status, oxidative stress index and lower total antioxidant status levels (p<0.001, p<0.001, p=0.001, p=0.008, respectively). Serum CP levels were significantly correlated with oxidative stress index levels (r=0.385, p=0.002). Conclusion. The present study demonstrated that both oxidative stress and CP levels increased in patients with PE, and increased CP levels seem to be a consequence of oxidative stress.en_US
dc.identifier.doi10.7417/CT.2013.1536
dc.identifier.endpageE87en_US
dc.identifier.issn0009-9074
dc.identifier.issn1972-6007
dc.identifier.issue2en_US
dc.identifier.pmid23698219
dc.identifier.startpageE83en_US
dc.identifier.urihttps://doi.org/10.7417/CT.2013.1536
dc.identifier.urihttps://hdl.handle.net/11468/20404
dc.identifier.volume164en_US
dc.identifier.wosWOS:000319320700002
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSoc Editrice Univen_US
dc.relation.ispartofClinica Terapeutica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCeruloplasminen_US
dc.subjectPreeclampsiaen_US
dc.subjectOxidative Stress Indexen_US
dc.subjectTotal Antioxidant Statusen_US
dc.subjectTotal Oxidant Statusen_US
dc.titleOxidative stress parameters and ceruloplasmin levels in patients with severe preeclampsiaen_US
dc.titleOxidative stress parameters and ceruloplasmin levels in patients with severe preeclampsia
dc.typeArticleen_US

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