β-Hydroxyamide-based ligands and their use in the enantioselective borane reduction of prochiral ketones

Basit Öğe Kaydı
dc.contributor.authorAzizoğlu, Murat
dc.contributor.authorErdoğan, Aslı
dc.contributor.authorArslan, Nevin
dc.contributor.authorTurgut, Yılmaz
dc.contributor.orcid0000-0003-0142-9215
dc.date.accessioned2024-04-24T15:59:22Z
dc.date.available2024-04-24T15:59:22Z
dc.date.issued2014
dc.departmentDicle Üniversitesi, Fen Fakültesi, Kimya Bölümüen_US
dc.description.abstractHydroxyamide-based ligands have occupied a considerable place in asymmetric synthesis. Here we report the synthesis of seven -hydroxyamide-based ligands from the reaction of 2-hydroxynicotinic acid with chiral amino alcohols and test their effect on the enantioselective reduction of aromatic prochiral ketones with borane in tetrahydofuran (THF). They produce the corresponding secondary alcohols with up to 76% enantiomeric excess (ee) and good to excellent yields (86-99%). Chirality 26:21-26, 2013. (c) 2013 Wiley Periodicals, Inc.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK) [110 T 809]en_US
dc.description.sponsorshipWe would like to thank the Scientific and Technological Research Council of Turkey (TUBITAK) for financially supporting this research (Project No: 110 T 809).en_US
dc.identifier.citationAzizoğlu, M., Erdoğan, A., Arslan, N. ve Turgut, Y. (2014). β-Hydroxyamide-based ligands and their use in the enantioselective borane reduction of prochiral ketones. Chirality, 26(1), 21-26.
dc.identifier.doi10.1002/chir.22254
dc.identifier.endpage26en_US
dc.identifier.issn0899-0042
dc.identifier.issn1520-636X
dc.identifier.issue1en_US
dc.identifier.pmid24203254
dc.identifier.scopus2-s2.0-84892435109
dc.identifier.scopusqualityQ2
dc.identifier.startpage21en_US
dc.identifier.urihttps://doi.org/10.1002/chir.22254
dc.identifier.urihttps://hdl.handle.net/11468/14014
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/10.1002/chir.22254
dc.identifier.volume26en_US
dc.identifier.wosWOS:000329437200003
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorAzizoğlu, Murat
dc.institutionauthorErdoğan, Aslı
dc.institutionauthorArslan, Nevin
dc.institutionauthorTurgut, Yılmaz
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofChirality
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHydroxyamideen_US
dc.subjectProchiral ketonesen_US
dc.subjectAsymmetric borane reductionen_US
dc.titleβ-Hydroxyamide-based ligands and their use in the enantioselective borane reduction of prochiral ketonesen_US
dc.title?-Hydroxyamide-based ligands and their use in the enantioselective borane reduction of prochiral ketones
dc.typeArticleen_US

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