Novel predictors of infarct-related artery patency for ST-segment elevation myocardial infarction: Platelet-to-lymphocyte ratio, uric acid, and neutrophil-to-lymphocyte ratio

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dc.authorid0000-0002-2145-9406en_US
dc.authorid0000-0002-1992-7848en_US
dc.authorid0000-0003-4326-6418en_US
dc.authorid0000-0003-2434-6690en_US
dc.authorid0000-0002-5090-7247en_US
dc.authorid0000-0001-7317-2979en_US
dc.contributor.authorAcet, Halit
dc.contributor.authorErtaş, Faruk
dc.contributor.authorAkıl, Mehmet Ata
dc.contributor.authorÖzyurtlu, Ferhat
dc.contributor.authorYıldız, Abdülkadir
dc.contributor.authorPolat, Nihat
dc.contributor.authorBilik, Mehmet Zihni
dc.contributor.authorAydın, Mesut
dc.contributor.authorOylumlu, Mustafa
dc.contributor.authorKaya, Hasan
dc.contributor.authorYüksel, Murat
dc.contributor.authorAkyüz, Abdurrahman
dc.contributor.authorAyçiçek, Hilal
dc.contributor.authorAlan, Sait
dc.contributor.authorToprak, Nizamettin
dc.date.accessioned2022-04-05T07:15:42Z
dc.date.available2022-04-05T07:15:42Z
dc.date.issued2015en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalıen_US
dc.description.abstractObjective: The neutrophil/lymphocyte ratio (NLR), the platelet/lymphocyte ratio (PLR), and uric acid (UA) are inflammatory markers in cardiovascular disease. However, there are not enough data on infarct-related artery (IRA) patency in ST-segment elevation myocardial infarction (STEMI). We aimed to investigate the association of NLR, PLR, and UA with IRA patency before percutaneous coronary intervention (PCI) in STEMI. Methods: The study was designed as a retrospective study. Three hundred and twenty-four consecutive patients with STEMI were divided into two groups according to pre-PCI Thrombolysis in Myocardial Infarction flow grade (TIMI). Patients with a TIMI flow grade of into the spontaneous reperfusion (SR) group, while patients with TIMI flow grade of 0, 1 and 2 were placed into the non-SR group. The χ2 and independentsamples t-test, Mann-Whitney U test, multivariate logistic regression analysis, and receiver-operator characteristic (ROC) curve analysis were used for the statistical analysis. Results: PLR, NLR, and UA values in the SR group were lower than in the non-SR group (p<0.004, p<0.001, p<0.001, respectively). In the multivariate analysis, serum UA level and PLR were found to be independent predictors of pre-PCI IRA patency. In the ROC curve analysis, PLR >190, UA>5.75 mg/dL, and NLR>4.2 predicted non-SR. The sensitivity and specificity of the association between low IRA TIMI flow grade and PLR were 88% and 84%, 72% and 66% for UA, and 74% and 44% for NLR, respectively. Conclusion: We determined that PLR and UA are novel predictors of IRA patency before PCI. We suggest that PLR and UA may be used in riskstratifying STEMI. (Anatol J Cardiol 2015; 15: 648-56)en_US
dc.identifier.citationAcet, H., Ertaş, F., Akıl, M. A., Özyurtlu, F., Yıldız, A., Polat, N. ve diğerleri. (2015). Novel predictors of infarct-related artery patency for ST-segment elevation myocardial infarction: Platelet-to-lymphocyte ratio, uric acid, and neutrophil-to-lymphocyte ratio. The Anatolian Journal of Cardiology, 15(8), 648-656.en_US
dc.identifier.doi10.5152/akd.2014.5592
dc.identifier.endpage656en_US
dc.identifier.issn2149-2263
dc.identifier.issn2149-2271
dc.identifier.issue8en_US
dc.identifier.pmid25550174
dc.identifier.scopus2-s2.0-84988451748
dc.identifier.scopusqualityQ3
dc.identifier.startpage648en_US
dc.identifier.trdizinid178017
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TVRjNE1ERTNOdz09
dc.identifier.urihttps://hdl.handle.net/11468/9520
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/178017
dc.identifier.volume15en_US
dc.identifier.wosWOS:000360292000011
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorAcet, Halit
dc.institutionauthorErtaş, Faruk
dc.institutionauthorAkıl, Mehmet Ata
dc.institutionauthorYıldız, Abdülkadir
dc.institutionauthorPolat, Nihat
dc.institutionauthorBilik, Mehmet Zihni
dc.institutionauthorAydın, Mesut
dc.institutionauthorOylumlu, Mustafa
dc.institutionauthorKaya, Hasan
dc.institutionauthorYüksel, Murat
dc.institutionauthorAkyüz, Abdurrahman
dc.institutionauthorAyçiçek, Hilal
dc.institutionauthorAlan, Sait
dc.institutionauthorToprak, Nizamettin
dc.language.isoenen_US
dc.publisherTurkish Society of Cardiologyen_US
dc.relation.ispartofThe Anatolian Journal of Cardiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPlatelet-to-lymphocyte ratioen_US
dc.subjectUric aciden_US
dc.subjectNeutrophil-to-lymphocyte ratioen_US
dc.subjectCoronary angiographyen_US
dc.subjectAcute myocardial infarctionen_US
dc.subjectInfarctrelated artery patencyen_US
dc.titleNovel predictors of infarct-related artery patency for ST-segment elevation myocardial infarction: Platelet-to-lymphocyte ratio, uric acid, and neutrophil-to-lymphocyte ratioen_US
dc.titleNovel predictors of infarct-related artery patency for ST-segment elevation myocardial infarction: Platelet-to-lymphocyte ratio, uric acid, and neutrophil-to-lymphocyte ratio
dc.typeArticleen_US

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