Light microscope evaluation of iron accumulation in term placentas of subjects with preeclampsia
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Tarih
2014
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Acta Medica Mediterranea
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Aims: In this study, the aim was to investigate if the the use of placental iron storages detection could be used. Materials and Methods: This study was performed on 30 placentas, 20 preeclamptic and 10 normal gestations, of 36 weeks or more. Paraffin sections of preeclamptic and normotensive placental tissues were stained with Hematoxylin and Eosin, Masson's Trichrome, and Prussian Blue. Results: Evaluation of preeclampsia group placentas showed as most common findings: increased syncytial node in villus, cytotrophoblast proliferation, increased volume and number of fetal capillary, and increased fibrinoid accumulation. Among preeclampsia group placental tissue samples, Prussian Blue staining was observed most commonly in fetal central cross-sections. In most prominently Prussian Blue stained villus, presence of syncytial nodes and close neighboring between iron accumulation and syncytial kodes ere interesting findings. Statistical analysis of data was made by SPSS software using Mann Whitney U test and p values under 0.05 ere accepted as statistically significant. Conclusion: Studies of placental light microscopy are important in the clarification of preeclampsia etiopathogenesis and more studies with wider scope are needed.
Açıklama
Anahtar Kelimeler
Iron Storage, Light Microscopy, Placenta, Preeclampsia
Kaynak
Acta Medica Mediterranea
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
30
Sayı
1