Assessment of serum alarin levels in patients with type 2 diabetes mellitus
Yükleniyor...
Tarih
2020
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Editura Acad Romane
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective. We aimed to investigate the potential
relationship between plasma alarin levels and type 2 diabetes
mellitus (T2DM).
Patients and Method. We included 154
participants, divided into four groups in a cross-sectional
study design. The first group includes patients with T2DM
without complications (n=30), the second group patients
with T2DM with microvascular complications (T2DMnoC n=32), the third group patients with T2DM with
macrovascular complications, T2DM-MV (n=32) and the
last group is the healthy control group (n=60).
Results. In our study 94 patients were diabetic;
47 females and 47 males. The control group consists of
60 people, 30 women and 30 men. It was found that these
had a significant (p>0.05) variation in serum alarin levels
among the T2DM (T2DM-noC=3.1±0.7 ng/mL T2DMmV=2.8±0.4 ng/mL, T2DM-MV= 3.6±0.4 ng/mL) versus
control group (15.6±2.6).
We failed to find a significant variation of serum
alarin levels (p>0.05) between T2DM subgroups. Serum
alarin levels were significantly higher among control
patients (p<0.05). There was no difference between diabetic
sub-groups.
Conclusion. We concluded that serum alarin
levels in patients with T2DM are lower than in normal
people. Further studies are needed to investigate the possible
prognostic value of alarin in clinical practice in T2DM.
Açıklama
WOS:000597111200007
PMID: 33029232
PMID: 33029232
Anahtar Kelimeler
Type 2 diabetes mellitus, Diabetic complications, Alarin level
Kaynak
Acta Endocrinologica (Bucharest)
WoS Q Değeri
Q4
Scopus Q Değeri
Q4
Cilt
16
Sayı
2
Künye
Kılınç, F., Demircan, F. Gözel, N., Önalan, E., Karataş, A., Pekkolay, Z. ve diğerleri. (2020). Assessment of serum alarin levels in patients with type 2 diabetes mellitus. Acta Endocrinologica (Bucharest), 16(2), 165-169.