Paramagnetic contribution of serum iron to the spin-lattice relaxation rate (1/T1) determined by MRI

[ X ]

Tarih

1998

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Springer Wien

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

T-1 maps of phantoms containing the samples of pure serum or Mn(II)-doped serum at pH = 2 were imaged by 1.5 T and 1 T MR Imagers. The T-1 measurements made for the determination of the paramagnetic increase were carried out before and after adding ascorbic acid. The difference of the 1/T-1 in samples with and without ascorbic acid was evaluated as the paramagnetic contribution (PMC) of serum iron. As iron content of serum varied from iron deficient to iron overload, the PMC values increased from 0.93 to 0.565 s(-1) at 1.5 T and from 0.103 to 0.609 s(-1) at 1 T For confirmative purposes, serum iron of each sample was determined from the paramagnetic contribution and also by an autoanalyzer. The contents of serum iron determined from PMC were in good agreement with those by the autoanalyzer and also with the literature. The data suggest that the paramagnetic contribution of serum iron can be measured by MRI.

Açıklama

Anahtar Kelimeler

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Kaynak

Applied Magnetic Resonance

WoS Q Değeri

Q3

Scopus Q Değeri

Q3

Cilt

14

Sayı

1

Künye