Electron spin resonance identification of gamma irradiated 2,4?-dichlorodiphenyl dichloroethane and 6-mercaptopurine monohydrate in the solid state

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dc.contributor.authorSutcu, Kerem
dc.contributor.authorOsmanoglu, Y. Emre
dc.date.accessioned2024-04-24T16:15:36Z
dc.date.available2024-04-24T16:15:36Z
dc.date.issued2018
dc.departmentDicle Üniversitesien_US
dc.description3rd International Turkish Congress on Molecular Spectroscopy (TURCMOS) -- AUG 26-29, 2017 -- Bodrum, TURKEYen_US
dc.description.abstractThe purpose of this study is to investigate the effects of ionizing radiation on two anticancer drugs, 2,4'-dichlorodiphenyl dichloroethane (DCP) and 6-mercaptopurine monohydrate (MPM), by using electron spin resonance (ESR) spectroscopy. For that purpose the intensity of ESR signals of the samples as a function of the microwave power was investigated in the range of 0.01-100 mW at room temperature. While unirradiated samples presented no ESR signal, irradiated samples exhibited significant ESR spectra. ESR measurements were performed at low and high temperatures to study the dosimetric features of free radicals induced by gamma irradiation. In order to obtain the dose-response curves, samples irradiated with gamma at 1, 5, 10, 15, 20, and 25 kGy dose values were used. Furthermore, the g values of the radicals and the hyperfine coupling constants were also determined. Additionally, the time dependency of the samples was analyzed to study the stability of the radicals. (C) 2018 Elsevier B.V. All rights reserved.en_US
dc.description.sponsorshipDicle University (DUBAP) [ZGEF.15.007]en_US
dc.description.sponsorshipThis work was supported by Grant No. ZGEF.15.007 of research Fund of Dicle University (DUBAP).en_US
dc.identifier.doi10.1016/j.molstruc.2018.02.048
dc.identifier.endpage73en_US
dc.identifier.issn0022-2860
dc.identifier.issn1872-8014
dc.identifier.scopus2-s2.0-85042049176
dc.identifier.scopusqualityQ1
dc.identifier.startpage67en_US
dc.identifier.urihttps://doi.org/10.1016/j.molstruc.2018.02.048
dc.identifier.urihttps://hdl.handle.net/11468/15864
dc.identifier.volume1174en_US
dc.identifier.wosWOS:000449132500011
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofJournal of Molecular Structure
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEsren_US
dc.subjectGamma-Irradiationen_US
dc.subjectFree Radicalsen_US
dc.titleElectron spin resonance identification of gamma irradiated 2,4?-dichlorodiphenyl dichloroethane and 6-mercaptopurine monohydrate in the solid stateen_US
dc.titleElectron spin resonance identification of gamma irradiated 2,4?-dichlorodiphenyl dichloroethane and 6-mercaptopurine monohydrate in the solid state
dc.typeConference Objecten_US

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