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Investigation of angucycline compounds as potential drug candidates against SARS Cov-2 main protease using docking and molecular dynamic approaches

Al-Bustany, Hazem Abbas; Ercan, Selami; İnce, Ebru; Pirinççioğlu, Necmettin (Springer, 2021)

The emerged Coronavirus disease (COVID-19) causes severe or even fatal respiratory tract infection, and to date there is no FDA-approved therapeutics or efective treatment available to efectively combat this viral infection. ...

Risk factors affecting ICU admission in COVID-19 patients; Could air temperature be an effective factor?

Solmaz, İhsan; Özçaylak, Süleyman; Alakuş, Ömer Faruk; Kılıç, Jehat; Kalın, Burhan Sami; Güven, Mehmet; Araç, Songül; Akkoç, Hasan (Wiley, 2021)

Aim As the COVID-19 pandemic has been spreading rapidly all over the world, there are plenty of ongoing works to shed on light to unknown factors related to disease. One of the factors questioned is also to be the factors ...

The effect of resistant hypertension on in-hospital mortality in patients hospitalized with COVID-19

Işık, Ferhat; Çap, Murat; Akyüz, Abdurrahman; Bilge, Önder; Aslan, Burhan; İnci, Ümit; Kaya, İlyas; Taştan, Ercan; Okşul, Metin; Çap, Neşe Kanbal; Karagöz, Ali; Baysal, Erkan (Springer Nature, 2021)

Hypertension is a major concomitant disease in hospitalized patients with COVID-19 (Coronavirus disease 2019) infection. The adverse effect of hypertension on prognosis in COVID-19 is known. Nevertheless, it is not known ...

Maternal and perinatal outcomes of pregnant women with SARS-CoV-2 infection

Saccone, Gabriele; Sen, Cihat; Di Mascio, Daniele; Galindo, Alberto; Grunebaum, Amos; Yoshimatsu, Jun; Stanojevic, Milan; Kurjak, Asim; Chervenak, Frank; Rodriguez Suarez, Maria Jose; Maria Gambacorti-Passerini, Zita; Anaya Baz, Maria de los Angeles; Aguilar Galan, Esther Vanessa; Cunarro Lopez, Yolanda; De Leon Luis, Juan Antonio; Cueto Hernandez, Ignacio; Herraiz, Ignacio; Villalain, Cecilia; Venturella, Roberta; Rizzo, Giuseppe; Mappa, Ilenia; Gerosolima, Giovanni; Hellmeyer, Lars; Koenigbauer, Josefine; Ameli, Giada; Frusca, Tiziana; Volpe, Nicola; Luca Schera, Giovanni Battista; Fieni, Stefania; Esposito, Eutalia; Simonazzi, Giuliana; Di Donna, Gaetana; Youssef, Aly; Della Gatta, Anna Nunzia; Di Donna, Mariano Catello; Chiantera, Vito; Buono, Natalina; Sozzi, Giulio; Greco, Pantaleo; Morano, Danila; Bianchi, Beatrice; Marino, Maria Giulia Lombana; Laraud, Federica; Ramone, Arianna; Cagnacci, Angelo; Barra, Fabio; Gustavino, Claudio; Ferrero, Simone; Ghezzi, Fabio; Cromi, Antonella; Lagana, Antonio Simone; Longo, Valentina Laurita; Stollagli, Francesca; Sirico, Angelo; Lanzone, Antonio; Driul, Lorenza; Cecchini, Fabiana; Xodo, Serena; Rodriguez, Brian; Mercado-Olivares, Felipe; Elkafrawi, Deena; Sisti, Giovanni; Esposito, Rosanna; Coviello, Antonio; Cerbone, Marco; Morlando, Maddalena; Schiattarella, Antonio; Colacurci, Nicola; De Franciscis, Pasquale; Cataneo, Ilaria; Lenzi, Marinella; Sandri, Fabrizio; Buscemi, Riccardo; Gattei, Giorgia; della Sala, Francesca; Valori, Eleonora; Rovellotti, Maria Cristina; Done, Elisa; Faron, Gilles; Gucciardo, Leonardo; Esposito, Valentina; Vena, Flaminia; Giancotti, Antonella; Brunelli, Roberto; Muzii, Ludovico; Nappi, Luigi; Sorrentino, Felice; Liberati, Marco; Buca, Danilo; Leombroni, Martina; Di Sebastiano, Francesca; Franchi, Massimo; Ianniciello, Quintino Cesare; Garzon, Simone; Petriglia, Giuliano; Borrello, Leonardo; Nieto-Calvache, Albaro Jose; Burgos-Luna, Juan Manuel; Kadji, Caroline; Carlin, Andrew; Bevilacqua, Elisa; Moucho, Marina; Pinto, Pedro Viana; Figueiredo, Rita; Morales Rosello, Jose; Loscalzo, Gabriela; Martinez-Varea, Alicia; Diago, Vincente; Jimenez Lopez, Jesus S.; Aykanat, Yeliz; Cosma, Stefano; Carosso, Andrea; Benedetto, Chiara; Bermejo, Amanda; May Feuerschuette, Otto Henrique; Uyaniklar, Ozlem; Ocakouglu, Sakine Rahimli; Atak, Zeliha; Gündüz, Reyhan; Haberal, Esra Tustas; Froessler, Bernd; Parange, Anupam; Palm, Peter; Samardjiski, Igor; Taccaliti, Chiara; Okuyan, Erhan; Daskalakis, George; Moreira de Sa, Renato Augusto; Pittaro, Alejandro; Gonzalez-Duran, Maria Luisa; Concheiro Guisan, Ana; Genc, Serife Ozlem; Zlatohlavkova, Blanka; Luengo Piqueras, Anna; Esteban Oliva, Dolores; Cil, Aylin Pelin; Api, Olus; Antsaklis, Panos; Ples, Liana; Kyvernitakis, Ioannis; Maul, Holger; Malan, Marcel; Lila, Albert; Granese, Roberta; Ercoli, Alfredo; Zoccali, Giuseppe; Villasco, Andrea; Biglia, Nicoletta; Madalina, Ciuhodaru; Costa, Elena; Daelemans, Caroline; Pintiaux, Axelle; Cueto, Elisa; Hadar, Eran; Dollinger, Sarah; Brzezinski-Sinai, Noa A.; Huertas, Erasmo; Arango, Pedro; Sanchez, Amadeo; Alfonso Schvartzman, Javier; Cojocaru, Liviu; Turan, Sifa; Turan, Ozhan; Di Dedda, Maria Carmela; Molpeceres, Rebeca Garrote; Zdjelar, Snezana; Premru-Srsen, Tanja; Kornhauser-Cerar, Lilijana; Druskovic, Miriam; De Robertis, Valentina; Stefanovic, Vedran; Nupponen, Irmeli; Nelskyla, Kaisa; Khodjaeva, Zulfiya; Gorina, Ksenia A.; Sukhikh, Gennady T.; Maruotti, Giuseppe Maria; Visentin, Silvia; Cosmi, Erich; Ferrari, Jacopo; Gatti, Alessandra; Luvero, Daniela; Angioli, Roberto; Puri, Ludovica; Palumbo, Marco; D'Urso, Giusella; Colaleo, Francesco; Rapisarda, Agnese Maria Chiara; Carbone, Ilma Floriana; Manzoli, Lamberto; Flacco, Maria Elena; Nazzaro, Giovanni; Locci, Mariavittoria; Guida, Maurizio; Sardo, Attilio Di Spiezio; Panici, Pierluigi Benedetti; Khalil, Asma; Berghella, Vincenzo; Bifulco, Giuseppe; Scambia, Giovanni; Zullo, Fulvio; D'Antonio, Francesco (Wiley, 2021)

Objectives To evaluate the maternal and perinatal outcomes of pregnancies affected by SARS-CoV-2 infection. Methods This was a multinational retrospective cohort study including women with a singleton pregnancy and ...

Impact of COVID-19 outbreak on patients with ST-segment elevation myocardial infarction (STEMI) in Turkey: results from TURSER study (TURKISH St-segment elevation myocardial infarction registry)

Kiris, Tuncay; Avcı, Eyüp; Ekin, Tuba; Akgün, Didar Elif; Tiryaki, Mücahit; Yidirim, Arafat; Hazır, Kutluhan; Murat, Bektaş; Yeni, Mehtap; Altındağ, Rojhad; Gül, Sefa; Arık, Baran; Güzel, Tuncay; Murat, Selda; Öz, Ahmet; Karabacak, Mustafa; Aktaş, Zihni; Yıldırım, Tarık; Kılıçaslan, Barış; Ergene, Asim Oktay (Springer, 2021)

Objective We aimed to investigate both the impact of COVID-19 pandemic on ST-segment elevation myocardial infarction (STEMI) admission, and demographic, angiographic, procedural characteristics, and in-hospital clinical ...

Cannabinoids for SARS-CoV-2 and is there evidence of their therapeutic efficacy?

Onay, Ahmet; Ertaş, Abdulselam; Süzerer, Veysel; Yener, İsmail; Yılmaz, Mustafa Abdullah; Ayaz-Tilkat, Emine; Ekinci, Remzi; Bozhan, Nesrin; İrtegun-Kandemir, Sevgi (Tubitak Scientific & Technical Research Council, 2021)

Abstract: To combat the coronaviruses and their novel variants, therapeutic drugs and the development of vaccines that are to be effective throughout human life are urgently needed. The endocannabinoid system (ECS) acts ...

Covid-19 sürecinde karantinaya yönelik tutum ölçeği: Türkçe uyarlama çalışması

Biçer, İsmail; Çakmak, Cuma; Göktepe, Esra Aydın; Kurt, Mehmet Emin (Dicle Üniversitesi Sosyal Bilimler Enstitüsü, 2021)

Çalışma, “Karantinaya Yönelik Tutum Ölçeği’nin Türkçe uyarlamasını yapmak, geçerlik ve güvenirlik analizlerini gerçekleştirmek amacıyla, metodolojik tasarım yöntemi ile yapılmıştır. Online anket yöntemiyle veri toplanmış ...

Determining similarities of COVID-19-lung cancer drugs and affinity binding mode analysis by graph neural network-based GEFA method

Budak, Cafer; Mençik, Vasfiye; Gider, Veysel (Taylor & Francis, 2021)

COVID-19 is a worldwide health crisis seriously endangering the arsenal of antiviral and antibiotic drugs. It is urgent to find an effective antiviral drug against pandemic caused by the severe acute respiratory syndrome ...

Acute necrotizing pancreatitis and coronavirus disease-2019 (COVID-19)

Aday, Ulaş; Gedik, Ercan; Kafadar, Mehmet Tolga; Özbek, Erdal (NLM (Medline), 2021)

Coronavirus disease-19 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV- 2) and has resulted in increased mortality worldwide. Several studies have identified the involvement of the ...

COVID-19 ve fiziksel tıp ve rehabilitasyon

Batmaz, İbrahim; Karakoç, Mehmet (Dicle Üniversitesi Tıp Fakültesi, 2021)

Koronavirüs Hastalığı 2019 (COVID-19); temelde solunum sistemi enfeksiyonu şeklinde hafif hastalıktan ciddi sepsis tablosuna kadar değişebilmektedir. Hastalık; kas-iskelet, nörolojik, kardiyopulmoner gibi farklı sistemik ...