Browsing by Author "Özkorkmaz, Ebru Gökalp"
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Biochemical and immunohistochemical investigations on bone formation and remodelling in ovariectomised rats with tamoxifen citrate administration
Baloǧlu, Murat; Özkorkmaz, Ebru Gökalp (Via Medica, 2019)Background: Osteoporosis results with the imbalance between osteoblastic formation and osteoclastic resorption, resulting in susceptibility to bone fractures. Ovariectomy leads to osteoporosis by triggering alterations in ... -
The effect of graft application and allopurinol treatmenon calvarial bone defect in rats
Laçin, Nihat; İzol, Bozan Serhat; Özkorkmaz, Ebru Gökalp; Deveci, Buşra; Tuncer, Cudi Mehmet (Sociedade Brasileira para o Desenvolvimento de Pesquisa em Cirurgia, 2019)Purpose: To investigate the effects of allopurinol administration on osteoinductive reaction and bone development with graft material. Methods: Thirty-six Wistar albino rats were divided into 3 groups. In the control ... -
The effect of graft application and simvastatin treatment on tibial bone defect in rats. A histological and immunohistochemical study
Laçin, Nihat; İzol, Bozan Serhat; Özkorkmaz, Ebru Gökalp; Deveci, Buşra; Tuncer, Cudi Mehmet (Sociedade Brasileira para o Desenvolvimento de Pesquisa em Cirurgia, 2019)Purpose: To evaluate histologically and immunohistochemically the bone regeneration after application of simvastatin on tibial bone defects in rats. Methods: Sixty Wistar albino rats were divided into 3 groups as control ... -
Effects of formaldehyde on vascular endothelial growth factor, matrix metallopeptidase 2 and osteonectin levels in periodontal membrane and alveolar bone in rats
Laçin, Nihat; İzol, Bozan Serhat; Tuncer, Cudi Mehmet; Özkorkmaz, Ebru Gokalp; Deveci, Buşra; Deveci, Engin (Via Medica, 2019)ackground: The objective of this study was to investigate whether long term formaldehyde inhalation may affect periodontal membrane and alveolar bone loss leading to periodontitis. The negative effects of formaldehyde were ... -
Neuroprotective effects of allopurinol on spinal cord injury in rats: A biochemical and immunohistochemical study
Baloǧlu, Murat; Özkorkmaz, Ebru Gökalp (Via Medica, 2019)Background: Lesion in spinal cord causes a cascade of events such as the apoptosis of neurons and eventually, neurological dysfunction. Neurologic damage developing after acute spinal cord injury is also related with ... -
Prolonged simvastatin treatment provided a decrease in apoptotic, inflammatory, and oxidative stress markers in ischemia-reperfusion-induced acute kidney injury model of rats
Kafkaslı, Alper; Özkorkmaz, Ebru Gökalp (Sci Printers & Publ INC, 2021)OBJECTIVE: Ischemia-reperfusion (I/R) leads to reactive oxygen species formation and cell death in kidney tissue with injury and organ transplantation. Simvastatin (SIM) is an antioxidant, anti-inflammatory, and anticoagulant ...
